Exploring plant-based materials to improve dental restorations
Modularity in Oligomeric Phenol Chemistry for Biomodulation of Dental Structures
['FUNDING_R21'] · UNIVERSITY OF ILLINOIS AT CHICAGO · NIH-10771302
This study is looking at new plant-based ingredients that could make dental adhesives and fillings stick better and last longer, which means better treatments for people with tooth decay.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT CHICAGO (nih funded) |
| Locations | 1 site (Chicago, UNITED STATES) |
| Trial ID | NIH-10771302 on ClinicalTrials.gov |
What this research studies
This research investigates the use of novel plant-derived compounds to enhance the effectiveness of dental adhesives and restorations. By focusing on specific classes of oligomeric phenols, the study aims to improve the bonding and longevity of dental materials used in treating tooth decay. The approach involves examining how these compounds interact with collagen in dentin, which is crucial for the structural integrity of teeth. Patients may benefit from improved dental treatments that last longer and perform better.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals undergoing dental procedures that involve restorations or adhesives for tooth decay.
Not a fit: Patients with no current dental issues or those who do not require restorative dental work may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more durable and effective dental restorations, reducing the need for repeat procedures.
How similar studies have performed: Previous research has shown promise in using plant-based materials for medical applications, suggesting potential success for this novel approach.
Where this research is happening
Chicago, UNITED STATES
- UNIVERSITY OF ILLINOIS AT CHICAGO — Chicago, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PAULI, GUIDO F — UNIVERSITY OF ILLINOIS AT CHICAGO
- Study coordinator: PAULI, GUIDO F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.