Exploring patient-supported methods for prenatal gene editing
PaSAGE: PAtient Supported Approaches to Gene Editing
This study is exploring new ways to safely edit genes before a baby is born to help prevent genetic diseases, and it wants to make sure that the opinions of families affected by these conditions are included in the conversation about how to do this responsibly.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project ID | NIH-11076897 on NIH RePORTER |
What this research studies
This research investigates new approaches to prenatal genetic editing aimed at preventing genetic diseases in unborn children. It focuses on developing governance structures that include the voices of patients and families affected by genetic conditions, ensuring ethical considerations are prioritized alongside technological advancements. The study seeks to address the gaps in current regulations surrounding gene editing practices in the United States, fostering a dialogue about the implications of these technologies. By engaging with stakeholders, the research aims to create a framework that balances innovation with ethical responsibility.
Who could benefit from this research
Good fit: Ideal candidates for this research include expectant parents or families with a history of genetic disorders who are considering prenatal genetic interventions.
Not a fit: Patients who are not expecting a child or those without a family history of genetic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more ethically guided practices for prenatal gene editing, potentially preventing genetic disorders before birth.
How similar studies have performed: While there have been discussions and preliminary research on prenatal gene editing, this approach to incorporating patient perspectives into governance is relatively novel and untested.
Where this research is happening
Jacksonville, United States
- Mayo Clinic Jacksonville — Jacksonville, United States (Active)
Researchers
- Principal investigator: Allyse, Megan a. — Mayo Clinic Jacksonville
- Study coordinator: Allyse, Megan a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.