Exploring pain management and psychological factors in critical limb ischemia

Pain Management Strategies, Associated Psychological Variables, and Outcomes in Critical Limb Ischemia

NIH-funded research Yale University · NIH-10599675

This study is looking at how different ways to manage pain and mental health support can help people with critical limb ischemia (CLI) feel better and improve their quality of life.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10599675 on NIH RePORTER

What this research studies

This research investigates how pain management strategies and psychological factors affect patients with critical limb ischemia (CLI), a severe condition that causes significant pain and can lead to amputation. The study aims to understand the relationship between different pain management approaches and patient outcomes over time, focusing on improving quality of life for those living with CLI. By integrating medical and psychological interventions, the research seeks to develop a comprehensive pain management program tailored to the needs of CLI patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with critical limb ischemia who experience chronic pain and are seeking better pain management solutions.

Not a fit: Patients who do not have critical limb ischemia or those who are not experiencing chronic pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved pain management strategies that enhance the quality of life for patients suffering from critical limb ischemia.

How similar studies have performed: Previous research has shown that integrated pain management approaches can be effective in improving outcomes for patients with chronic pain conditions, suggesting potential success for this study.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.