Exploring pain management and psychological factors in critical limb ischemia
Official title: Pain Management Strategies, Associated Psychological Variables, and Outcomes in Critical Limb Ischemia
Funded at Yale University · NIH-10599675 · Data updated 2026-11-12
This study is looking at how different ways to manage pain and mental health support can help people with critical limb ischemia (CLI) feel better and improve their quality of life.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 19, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $460,625 |
| NIH project number | 1R21AT012430-01 |
| Project ID | NIH-10599675 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with critical limb ischemia who experience chronic pain and are seeking better pain management solutions.
✕Less likely to help
Patients who do not have critical limb ischemia or those who are not experiencing chronic pain may not benefit from this research.
What this research studies
This research investigates how pain management strategies and psychological factors affect patients with critical limb ischemia (CLI), a severe condition that causes significant pain and can lead to amputation. The study aims to understand the relationship between different pain management approaches and patient outcomes over time, focusing on improving quality of life for those living with CLI. By integrating medical and psychological interventions, the research seeks to develop a comprehensive pain management program tailored to the needs of CLI patients.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies that enhance the quality of life for patients suffering from critical limb ischemia.
How similar studies have gone: Previous research has shown that integrated pain management approaches can be effective in improving outcomes for patients with chronic pain conditions, suggesting potential success for this study.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Smolderen, Kim Germaine — Yale University
- Study coordinator: Smolderen, Kim Germaine
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.