Exploring new ways to treat bacterial vaginosis using innovative delivery methods.
Understanding the Host-Microbiome-Therapeutic Triad: Implications for Designing Alternative Intravaginal Delivery Platforms to Treat Bacterial Vaginosis
This study is looking at new ways to treat bacterial vaginosis (BV) by using different methods to deliver helpful treatments like probiotics, so women can have easier and more effective options to restore their vaginal health and reduce the chances of BV coming back.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Louisville NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project ID | NIH-10652467 on NIH RePORTER |
What this research studies
This research focuses on bacterial vaginosis (BV), a condition affecting about 30% of women in the U.S. that disrupts the natural balance of bacteria in the vagina. The study aims to develop new therapeutic approaches that utilize alternative intravaginal delivery systems to effectively administer treatments like probiotics and lactic acid. By understanding the interactions between the host, microbiome, and delivery methods, the research seeks to create more effective and convenient treatment options for BV, reducing the risk of recurrence and associated complications. Patients may benefit from improved therapies that are easier to use and more effective in restoring healthy vaginal flora.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing recurrent bacterial vaginosis or those at risk for this condition.
Not a fit: Patients who do not have bacterial vaginosis or are not at risk for developing it may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and convenient treatments for bacterial vaginosis, reducing recurrence rates and improving women's health outcomes.
How similar studies have performed: Previous research has shown promise in using probiotics and alternative delivery methods for treating bacterial vaginosis, indicating potential for success in this innovative approach.
Where this research is happening
Louisville, United States
- University of Louisville — Louisville, United States (Active)
Researchers
- Principal investigator: Frieboes, Hermann — University of Louisville
- Study coordinator: Frieboes, Hermann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.