Exploring new ways to repair heart damage
Targeting Pathways Involved in Cardiac Injury for Novel Repair Strategies
This study is looking at how heart failure happens and how the heart talks to other organs, like the kidneys, to find new ways to help people with heart problems feel better.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10831434 on NIH RePORTER |
What this research studies
This research focuses on understanding the mechanisms behind heart failure, a condition that arises from cardiac injury and stress. The team aims to identify specific signaling pathways involved in heart injury and repair, using innovative mouse models to test their hypotheses. By investigating how the failing heart communicates with other organs, such as the kidneys, the research seeks to uncover new therapeutic strategies that could improve treatment options for patients suffering from heart failure and related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with heart failure or those experiencing cardiac injury.
Not a fit: Patients with stable heart conditions or those not experiencing cardiac injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to groundbreaking therapies that significantly improve outcomes for patients with heart failure and related syndromes.
How similar studies have performed: Previous research has shown promise in targeting similar pathways for cardiac repair, indicating that this approach could yield significant advancements.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Koch, Walter J. — Duke University
- Study coordinator: Koch, Walter J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.