Exploring new ways to combine amines and acids for drug development

New Amine-Acid Couplings and Their Impact on Medicinal Properties

NIH-funded research University of Michigan at Ann Arbor · NIH-11083771

This study is exploring new ways to mix certain chemicals to create better medicines, which could lead to more effective treatments for patients like you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11083771 on NIH RePORTER

What this research studies

This research investigates innovative chemical reactions that combine amines and acids to create new drug-like compounds. By utilizing a diverse range of reactions rather than relying on traditional methods, the project aims to enhance the efficiency and effectiveness of drug discovery. The approach includes both theoretical and experimental development of these new coupling reactions, focusing on forming carbon-carbon bonds that are crucial in pharmaceuticals. Patients may benefit from the development of more effective medications resulting from these novel chemical processes.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be individuals with conditions that could be treated by new drug compounds developed through these innovative chemical reactions.

Not a fit: Patients who are not seeking new treatment options or who do not have conditions that could be addressed by the new drugs developed may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the creation of more effective and diverse medications for various health conditions.

How similar studies have performed: While this approach is innovative, similar research has shown promise in enhancing drug discovery through novel chemical reactions.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.