Exploring new treatments to help cure HIV.

Clinical Pharmacology Approaches towards Accelerating HIV Cure Initiatives

NIH-funded research University of California, San Francisco · NIH-10892164

This study is exploring new ways to help people with HIV live without needing daily medication by testing different drugs and vaccines to see how they can boost the immune system and fight the virus more effectively.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10892164 on NIH RePORTER

What this research studies

This research focuses on developing new pharmacological approaches to achieve a functional cure for HIV, allowing patients to live without antiretroviral therapy. It aims to understand how different drugs affect the immune system and viral persistence in people living with HIV. The project includes clinical trials testing the effectiveness of sirolimus and a vaccine, as well as novel antibodies that target the virus. By addressing the variability in drug responses, the research seeks to create more effective and personalized treatment options for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who are seeking new treatment options or are interested in participating in clinical trials.

Not a fit: Patients who are not living with HIV or those who are not eligible for clinical trials due to specific health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that allow people living with HIV to maintain their health without the need for continuous antiretroviral therapy.

How similar studies have performed: Previous research has shown promise in using novel therapeutic approaches for HIV, but this specific combination of treatments is being explored for the first time.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.