Exploring new treatments for low back pain in military veterans
Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial
This study is looking at whether two new treatments can help relieve chronic low back pain in US military veterans, without the risks of traditional pain medications, by comparing them to a placebo in a way that keeps everyone guessing which one they’re getting.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Durham VA Medical Center NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11044060 on NIH RePORTER |
What this research studies
This research investigates the safety and effectiveness of two neurosteroid molecules as potential treatments for chronic low back pain specifically in US military veterans. The study employs a randomized, double-blind, placebo-controlled design, meaning that participants will be randomly assigned to receive either the treatment or a placebo without knowing which they are receiving. The goal is to determine if these neurosteroids can provide relief from pain without the risks associated with traditional opioid medications. By focusing on veterans, the research aims to address a critical need for effective pain management in this population.
Who could benefit from this research
Good fit: Ideal candidates for participation are US military veterans suffering from chronic low back pain.
Not a fit: Patients who do not have chronic low back pain or are not military veterans may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, non-addictive treatments for chronic low back pain, improving the quality of life for veterans.
How similar studies have performed: Previous research has shown promising results with neurosteroids in pain management, indicating potential for success in this study.
Where this research is happening
Durham, United States
- Durham VA Medical Center — Durham, United States (Active)
Researchers
- Principal investigator: Naylor, Jennifer C — Durham VA Medical Center
- Study coordinator: Naylor, Jennifer C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.