Exploring new treatments for depression in patients with chronic kidney disease.
Combination of Novel Therapies for CKD Comorbid Depression (CONCORD)
This study is looking at whether treating depression can help people with chronic kidney disease feel better and improve their health, by testing new treatment options to see if they work better than what’s currently available.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-11014579 on NIH RePORTER |
What this research studies
This research investigates whether treating Major Depressive Disorder (MDD) can improve health outcomes for patients suffering from chronic kidney disease (CKD). It recognizes that a significant number of CKD patients also experience depression, which can worsen their kidney condition and overall quality of life. The study will compare the effectiveness and tolerability of two novel treatment strategies against a control group, aiming to provide better options for managing depression in this population. By focusing on innovative therapies, the research seeks to address the limitations of existing treatments that have shown little success in CKD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic kidney disease who also have Major Depressive Disorder.
Not a fit: Patients without chronic kidney disease or those who do not have Major Depressive Disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved mental health and physical outcomes for CKD patients suffering from depression.
How similar studies have performed: Previous studies have shown limited success with conventional antidepressant treatments in CKD patients, highlighting the need for novel approaches like this one.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Hedayati, Susan — State University New York Stony Brook
- Study coordinator: Hedayati, Susan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.