Exploring new targets for diagnosing and treating Alzheimer's disease
Official title: Sialoglycoproteomic network and target discovery for Alzheimer's disease
Funded at Emory University · NIH-10906196 · Data updated 2026-11-12
This study is looking at how certain proteins in the brain change in Alzheimer's disease to help find new ways to diagnose and treat the condition, which could lead to better care for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | August 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $769,621 |
| NIH project number | 5R01AG079836-02 |
| Project ID | NIH-10906196 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for Alzheimer's disease or those experiencing early symptoms of dementia.
✕Less likely to help
Patients with advanced Alzheimer's disease or other forms of dementia unrelated to Alzheimer's may not benefit from this research.
What this research studies
This research investigates the role of protein sialylation in Alzheimer's disease, aiming to uncover new molecular targets for early diagnosis and intervention. By studying how sialic acids affect protein interactions and brain function, the project seeks to identify potential biomarkers and therapeutic targets. Patients may benefit from advancements in diagnostic methods and treatment options that arise from a deeper understanding of the disease mechanisms involved. The research employs advanced biochemical techniques to analyze sialoglycoproteins and their implications in Alzheimer's pathology.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for Alzheimer's disease.
How similar studies have gone: Previous research has shown promise in targeting molecular pathways related to Alzheimer's disease, suggesting that this approach may yield significant insights.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Li, Lian — Emory University
- Study coordinator: Li, Lian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.