Exploring new small molecules to enhance tissue repair and stress response.
Methods and approaches to expand the pharmacological toolset
['FUNDING_OTHER'] · SCRIPPS RESEARCH INSTITUTE, THE · NIH-10861090
This study is looking for new ways to help your body heal better and faster by finding small molecules that can boost tissue repair and help cells handle stress, which could lead to better treatments for conditions that affect healing.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SCRIPPS RESEARCH INSTITUTE, THE (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10861090 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying small molecules that can promote tissue repair and improve cellular responses to stress. By targeting specific pathways involved in regenerative medicine, such as the Hippo YAP pathway, the researchers aim to develop new treatments that can enhance healing. The project also investigates how cells respond to various stressors, including heat shock and oxidative stress, to create innovative therapeutic agents. Patients may benefit from advancements in regenerative therapies and improved treatments for conditions related to cellular stress.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that impair tissue regeneration or those affected by cellular stress-related diseases.
Not a fit: Patients with conditions unrelated to tissue repair or cellular stress responses may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve tissue repair and stress response in patients.
How similar studies have performed: Previous research has shown promise in developing small molecules targeting cellular stress responses, indicating potential for success in this area.
Where this research is happening
LA JOLLA, UNITED STATES
- SCRIPPS RESEARCH INSTITUTE, THE — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOLLONG, MICHAEL J — SCRIPPS RESEARCH INSTITUTE, THE
- Study coordinator: BOLLONG, MICHAEL J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.