Exploring new RNA structures in viruses
Finding and folding novel RNA structures
This study is looking at the RNA structures in viruses like the coronavirus to find new ways to develop treatments, which could help patients dealing with viral infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Iowa State University NIH-funded |
| Lab location | 1 site (Ames, United States) |
| Project ID | NIH-10877610 on NIH RePORTER |
What this research studies
This research investigates the functional aspects of RNA structures found in human pathogenic viruses, particularly focusing on the novel coronavirus. By employing a two-step methodology, the researchers first scan long RNA sequences to predict structure-related metrics and then generate consensus structures to identify stable RNA formations. This approach aims to uncover regulatory RNA structures that could be targeted for therapeutic development, potentially leading to new treatments for viral infections. Patients may benefit from advancements in RNA-targeted therapies that arise from this work.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals affected by viral infections, particularly those caused by coronaviruses.
Not a fit: Patients with non-viral infections or those not affected by RNA-related diseases may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new RNA-targeted therapies for viral infections, including COVID-19.
How similar studies have performed: Previous research has shown success in identifying functional RNA structures in other human pathogens, indicating a promising approach for this study.
Where this research is happening
Ames, United States
- Iowa State University — Ames, United States (Active)
Researchers
- Principal investigator: Moss, Walter — Iowa State University
- Study coordinator: Moss, Walter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.