Exploring new proteins involved in chronic pain
Lymphocyte Antigen 6 (Ly6) Proteins: New Players in Chronic Pain
This study is looking at how certain proteins called Ly6 might affect pain signals in the body, which could help us find new ways to treat chronic pain for people who suffer from it.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11072836 on NIH RePORTER |
What this research studies
This research investigates the role of lymphocyte antigen 6 (Ly6) proteins in chronic pain, focusing on how these proteins may influence the functioning of a key sodium channel involved in pain signaling. By studying the interactions and regulation of these proteins, the research aims to uncover new mechanisms that contribute to the hyperexcitability of sensory neurons in chronic pain conditions. The approach includes genetic and functional studies to better understand how Ly6 proteins modulate pain pathways, potentially leading to new therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic pain conditions.
Not a fit: Patients with acute pain or those not experiencing chronic pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for chronic pain by targeting the mechanisms involving Ly6 proteins.
How similar studies have performed: While the specific role of Ly6 proteins in chronic pain is novel, similar approaches targeting sodium channels have shown promise in other studies.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Gomez, Kimberly — University of Florida
- Study coordinator: Gomez, Kimberly
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.