Exploring new proteins involved in chronic pain
Official title: Lymphocyte Antigen 6 (Ly6) Proteins: New Players in Chronic Pain
Funded at University of Florida · NIH-11072836 · Data updated 2026-11-12
This study is looking at how certain proteins called Ly6 might affect pain signals in the body, which could help us find new ways to treat chronic pain for people who suffer from it.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 25, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $233,701 |
| NIH project number | 7K99NS134965-02 |
| Project ID | NIH-11072836 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from chronic pain conditions.
✕Less likely to help
Patients with acute pain or those not experiencing chronic pain may not benefit from this research.
What this research studies
This research investigates the role of lymphocyte antigen 6 (Ly6) proteins in chronic pain, focusing on how these proteins may influence the functioning of a key sodium channel involved in pain signaling. By studying the interactions and regulation of these proteins, the research aims to uncover new mechanisms that contribute to the hyperexcitability of sensory neurons in chronic pain conditions. The approach includes genetic and functional studies to better understand how Ly6 proteins modulate pain pathways, potentially leading to new therapeutic targets.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for chronic pain by targeting the mechanisms involving Ly6 proteins.
How similar studies have gone: While the specific role of Ly6 proteins in chronic pain is novel, similar approaches targeting sodium channels have shown promise in other studies.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Gomez, Kimberly — University of Florida
- Study coordinator: Gomez, Kimberly
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.