Exploring new platinum-gold compounds for treating ovarian cancer
Official title: Platinum-Gold Compounds as Potential Chemo- and Targeted Agents for Ovarian Cancer
Funded at Brooklyn College · NIH-10899422 · Data updated 2026-11-12
This study is exploring new treatment options for ovarian cancer using special platinum-gold compounds that might work better and cause fewer side effects for patients who haven't responded to standard chemotherapy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brooklyn College NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 4, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $162,366 |
| NIH project number | 5R16GM149396-02 |
| Project ID | NIH-10899422 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with advanced ovarian cancer, particularly those who have not responded well to standard platinum-based therapies.
✕Less likely to help
Patients with early-stage ovarian cancer or those who have not undergone chemotherapy may not benefit from this research.
What this research studies
This research investigates the potential of modified platinum-gold compounds as new treatment options for ovarian cancer, particularly for patients who have developed resistance to standard platinum-based chemotherapy. The approach focuses on developing these compounds to improve their effectiveness and reduce side effects compared to existing treatments. By targeting cancer cells more selectively, the goal is to enhance the therapeutic outcomes for patients suffering from advanced stages of ovarian cancer. The study will involve laboratory testing to evaluate the efficacy and safety of these new agents.
Why it matters
Potential benefit: If successful, this research could lead to more effective and less toxic treatment options for ovarian cancer patients.
How similar studies have gone: While the use of platinum-based compounds is well-established, the specific approach of combining platinum with gold derivatives is novel and has not been extensively tested in clinical settings.
Where this research is happening
-
Brooklyn College
New York, United States Active
Researchers
- Principal investigator: Contel, Maria — Brooklyn College
- Study coordinator: Contel, Maria
Related research
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-
Integrated framework to validate and quantify proteoforms in patient-derived ovarian cancer cells
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Overcoming platinum resistance in ovarian cancer: finding biomarkers and new targets
Researchers are looking for new biomarkers and targets to help prevent or overcome platinum resistance in high‑risk ovarian cancer so patients have better chances at long-term control.
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Alternative NF-kB activation after chemotherapy in ovarian cancer
This grant studies how ovarian cancer might come back after chemotherapy by looking at specific signaling pathways in cancer cells and the tumor environment.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.