Exploring new heme chemistry in bacteria
Uncovering novel heme chemistry in microbial systems
['FUNDING_OTHER'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-11020809
This study is looking at special proteins that help our bodies with energy and cleaning up toxins, to see how they can be used to create new medicines and improve drug detoxification for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded) |
| Locations | 1 site (CHAMPAIGN, UNITED STATES) |
| Trial ID | NIH-11020809 on ClinicalTrials.gov |
What this research studies
This research investigates the role of heme-containing metalloenzymes in various biological processes, such as energy conversion and detoxification. By studying these enzymes, the project aims to uncover their potential applications in producing pharmaceuticals and industrial chemicals. The research utilizes genomic data to explore previously uncharacterized heme proteins, focusing on their biochemical properties and functional roles. Patients may benefit from advancements in drug detoxification and the development of new medications derived from these enzymes.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions related to drug metabolism or those requiring novel therapeutic options.
Not a fit: Patients with conditions unrelated to drug metabolism or those not requiring new pharmaceutical interventions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved drug detoxification methods and the development of new pharmaceuticals.
How similar studies have performed: Other research has shown promise in utilizing metalloenzymes for drug detoxification and chemical synthesis, indicating a potential for success in this area.
Where this research is happening
CHAMPAIGN, UNITED STATES
- UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN — CHAMPAIGN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MANESIS, ANASTASIA — UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
- Study coordinator: MANESIS, ANASTASIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cellular injury, Conversion disorder