Exploring new heme chemistry in bacteria
Official title: Uncovering novel heme chemistry in microbial systems
Funded at University of Illinois at Urbana-Champaign · NIH-11020809 · Data updated 2026-11-12
This study is looking at special proteins that help our bodies with energy and cleaning up toxins, to see how they can be used to create new medicines and improve drug detoxification for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Urbana-Champaign NIH-funded |
| Lab location | 1 site (Champaign, United States) |
| Project start | September 15, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $350,487 |
| NIH project number | 1R35GM157008-01 |
| Project ID | NIH-11020809 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with conditions related to drug metabolism or those requiring novel therapeutic options.
✕Less likely to help
Patients with conditions unrelated to drug metabolism or those not requiring new pharmaceutical interventions may not benefit from this research.
What this research studies
This research investigates the role of heme-containing metalloenzymes in various biological processes, such as energy conversion and detoxification. By studying these enzymes, the project aims to uncover their potential applications in producing pharmaceuticals and industrial chemicals. The research utilizes genomic data to explore previously uncharacterized heme proteins, focusing on their biochemical properties and functional roles. Patients may benefit from advancements in drug detoxification and the development of new medications derived from these enzymes.
Why it matters
Potential benefit: If successful, this research could lead to improved drug detoxification methods and the development of new pharmaceuticals.
How similar studies have gone: Other research has shown promise in utilizing metalloenzymes for drug detoxification and chemical synthesis, indicating a potential for success in this area.
Where this research is happening
-
University of Illinois at Urbana-Champaign
Champaign, United States Active
Researchers
- Principal investigator: Manesis, Anastasia — University of Illinois at Urbana-Champaign
- Study coordinator: Manesis, Anastasia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.