Exploring new genes and networks in pulmonary arterial hypertension
Official title: Integrative Multiomics to Uncover Novel Genes and Networks in Pulmonary Arterial Hypertension
Funded at University of California Los Angeles · NIH-10903844 · Data updated 2026-11-12
This study is looking at the genes and molecules involved in pulmonary arterial hypertension (PAH) by examining lung samples from both PAH patients and healthy individuals, with the goal of finding new ways to treat the condition and help patients feel better.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | August 10, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $176,580 |
| NIH project number | 5K08HL169982-02 |
| Project ID | NIH-10903844 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with pulmonary arterial hypertension.
✕Less likely to help
Patients with other forms of pulmonary hypertension or unrelated cardiovascular conditions may not benefit from this research.
What this research studies
This research investigates the genetic and molecular underpinnings of pulmonary arterial hypertension (PAH) using an integrative multiomics approach. By analyzing a large biobank of lung samples from PAH patients and healthy controls, the study aims to identify novel genes and networks that contribute to the disease. The research employs advanced techniques such as RNA sequencing and computational analysis to uncover potential therapeutic targets. Patients may benefit from the development of more effective treatments based on these findings.
Why it matters
Potential benefit: If successful, this research could lead to more effective targeted therapies for patients suffering from pulmonary arterial hypertension.
How similar studies have gone: Previous research using multiomics approaches has shown promise in identifying genetic factors in various diseases, suggesting potential success for this novel approach in PAH.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Hong, Jason — University of California Los Angeles
- Study coordinator: Hong, Jason
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.