Exploring new genes and networks in pulmonary arterial hypertension
Integrative Multiomics to Uncover Novel Genes and Networks in Pulmonary Arterial Hypertension
This study is looking at the genes and molecules involved in pulmonary arterial hypertension (PAH) by examining lung samples from both PAH patients and healthy individuals, with the goal of finding new ways to treat the condition and help patients feel better.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10903844 on NIH RePORTER |
What this research studies
This research investigates the genetic and molecular underpinnings of pulmonary arterial hypertension (PAH) using an integrative multiomics approach. By analyzing a large biobank of lung samples from PAH patients and healthy controls, the study aims to identify novel genes and networks that contribute to the disease. The research employs advanced techniques such as RNA sequencing and computational analysis to uncover potential therapeutic targets. Patients may benefit from the development of more effective treatments based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pulmonary arterial hypertension.
Not a fit: Patients with other forms of pulmonary hypertension or unrelated cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective targeted therapies for patients suffering from pulmonary arterial hypertension.
How similar studies have performed: Previous research using multiomics approaches has shown promise in identifying genetic factors in various diseases, suggesting potential success for this novel approach in PAH.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Hong, Jason — University of California Los Angeles
- Study coordinator: Hong, Jason
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.