Exploring new compounds to enhance a viral therapy for breast cancer treatment
Development of natural and synthetic compounds as novel potentiators of HSV-1 VC2-GMCSF-based oncolytic viral therapy in Breast Cancer
This study is exploring new ways to make a special virus treatment for aggressive breast cancer work better, and it could help patients by using both natural and man-made compounds to boost the therapy's effectiveness.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ A&m Col Baton Rouge NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project ID | NIH-11247897 on NIH RePORTER |
What this research studies
This research focuses on developing both natural and synthetic compounds that can improve the effectiveness of a specific viral therapy targeting breast cancer, particularly the aggressive triple-negative subtype. The approach involves using oncolytic viruses, which are engineered to selectively infect and destroy cancer cells while sparing healthy cells. By inhibiting certain cancer-related signaling pathways, the researchers aim to create a more favorable environment for the viral therapy to work effectively. Patients may benefit from this innovative treatment strategy that combines virology and cancer biology.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with triple-negative breast cancer who have limited treatment options.
Not a fit: Patients with non-breast cancer diagnoses or those with early-stage breast cancer may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for patients with breast cancer, particularly those with triple-negative breast cancer.
How similar studies have performed: Previous research has shown promise in using oncolytic viruses for cancer treatment, indicating that this approach may be viable and beneficial.
Where this research is happening
Baton Rouge, United States
- Louisiana State Univ A&m Col Baton Rouge — Baton Rouge, United States (Active)
Researchers
- Principal investigator: Chamcheu, Jean Christopher — Louisiana State Univ A&m Col Baton Rouge
- Study coordinator: Chamcheu, Jean Christopher
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.