Exploring new chemical compounds using boron and nitrogen
Official title: Expanding the Chemical and Functional Space with Boron-Nitrogen Heterocycles
Funded at Boston College · NIH-10842874 · Data updated 2026-11-12
This study is looking at new ways to create different kinds of chemical compounds that could lead to better drugs and treatments for patients by using boron-nitrogen bonds instead of the usual carbon-carbon bonds.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston College NIH-funded |
| Lab location | 1 site (Chestnut Hill, United States) |
| Project start | September 10, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $387,500 |
| NIH project number | 1R35GM153328-01 |
| Project ID | NIH-10842874 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with conditions that could be treated with new therapeutic agents derived from these novel compounds.
✕Less likely to help
Patients with conditions that are not addressed by the types of compounds being developed in this research may not receive any benefit.
What this research studies
This research focuses on expanding the types of chemical compounds that can be created by replacing carbon-carbon bonds with boron-nitrogen bonds. By doing so, the researchers aim to discover new reactions and selectivities that are not possible with traditional organic compounds. The project will also explore the creation of novel proteins and bioconjugation methods that could enhance our understanding of biological processes. Patients may benefit from advancements in drug development and therapeutic strategies that arise from these new compounds.
Why it matters
Potential benefit: If successful, this research could lead to the development of innovative drugs and therapies that improve patient outcomes.
How similar studies have gone: Other research has shown promise in expanding chemical space through similar approaches, indicating potential for success in this novel area.
Where this research is happening
-
Boston College
Chestnut Hill, United States Active
Researchers
- Principal investigator: Liu, Shih-Yuan — Boston College
- Study coordinator: Liu, Shih-Yuan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.