Exploring new biomarkers for Alzheimer's Disease through signaling pathways
Dissecting signaling pathways and seeking EV phosphoproteins as novel biomarkers for Alzheimer's Disease
['FUNDING_R01'] · PURDUE UNIVERSITY · NIH-10875742
This study is looking at how certain proteins in your blood might help doctors spot Alzheimer's disease earlier, which could lead to better ways to manage the condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PURDUE UNIVERSITY (nih funded) |
| Locations | 1 site (WEST LAFAYETTE, UNITED STATES) |
| Trial ID | NIH-10875742 on ClinicalTrials.gov |
What this research studies
This research investigates the underlying molecular mechanisms of Alzheimer's Disease (AD) by focusing on the signaling pathways involved in its progression. Researchers aim to identify and validate specific proteins in blood that could serve as biomarkers for early diagnosis of AD. By analyzing extracellular vesicles and their phosphorylated proteins, the study seeks to uncover critical relationships between these proteins and the disease's pathology. Patients may benefit from improved diagnostic methods that could lead to earlier detection and better management of Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's Disease or those experiencing early symptoms of cognitive decline.
Not a fit: Patients with advanced Alzheimer's Disease or those without any cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of reliable biomarkers for early diagnosis of Alzheimer's Disease.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for Alzheimer's Disease, suggesting that this approach could yield valuable insights.
Where this research is happening
WEST LAFAYETTE, UNITED STATES
- PURDUE UNIVERSITY — WEST LAFAYETTE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TAO, W. ANDY — PURDUE UNIVERSITY
- Study coordinator: TAO, W. ANDY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer disease detection, Alzheimer syndrome, Alzheimer's Disease