Exploring natural products to discover new drugs using big data analysis.
Accessing and Expanding Natural Products Chemical Diversity by Big-data Analysis and Biosynthetic Investigation
This study is looking for new natural substances that could be turned into medicines by exploring genetic information, which might lead to new treatments that could help patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Carolina at Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project ID | NIH-10907760 on NIH RePORTER |
What this research studies
This research focuses on uncovering new bioactive natural products that can be developed into drugs. By analyzing vast amounts of genetic data, the team aims to identify previously overlooked gene clusters that could produce unique compounds. The approach combines advanced informatics with biosynthetic investigations to connect these gene clusters to their potential products, ultimately expanding the diversity of available natural products for drug discovery. Patients may benefit from new medications derived from these discoveries.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions that could be treated by novel drugs derived from natural products.
Not a fit: Patients who are not seeking new treatment options or those with conditions not addressed by natural product-derived medications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and effective medications derived from previously untapped natural products.
How similar studies have performed: Other research has shown success in utilizing big data and biosynthetic investigations to discover new natural products, indicating a promising approach.
Where this research is happening
Columbia, United States
- University of South Carolina at Columbia — Columbia, United States (Active)
Researchers
- Principal investigator: Li, Jie — University of South Carolina at Columbia
- Study coordinator: Li, Jie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.