Exploring metalloproteins for new treatments and materials
Official title: Metalloproteins: evolution, catalysis and material design
Funded at Baylor University · NIH-10941277 · Data updated 2026-11-12
This study is exploring how certain proteins can help create better treatments for joint pain, like osteoarthritis, by making new materials and enzymes that work more effectively, all while using advanced technology to understand how these proteins move and change.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor University NIH-funded |
| Lab location | 1 site (Waco, United States) |
| Project start | September 5, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $235,959 |
| NIH project number | 1R35GM155013-01 |
| Project ID | NIH-10941277 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit include individuals suffering from osteoarthritis or those interested in advancements in biocompatible materials.
✕Less likely to help
Patients with conditions unrelated to osteoarthritis or those not seeking innovative treatment options may not benefit from this research.
What this research studies
This research investigates the role of metalloproteins in catalysis and material design, focusing on how protein dynamics can lead to productive mutations. By utilizing advanced techniques like NMR spectroscopy, the project aims to create efficient metalloenzymes and develop innovative hydrogels for treating osteoarthritis. The approach combines fundamental science with practical applications, including the creation of biocompatible catalysts for environmental remediation and improved treatments for joint diseases.
Why it matters
Potential benefit: If successful, this research could lead to new, effective treatments for osteoarthritis and innovative materials for various applications.
How similar studies have gone: Previous research has shown promise in using metalloproteins for catalysis and treatment applications, indicating a potential for success in this novel approach.
Where this research is happening
-
Baylor University
Waco, United States Active
Researchers
- Principal investigator: Makhlynets, Olga — Baylor University
- Study coordinator: Makhlynets, Olga
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.