Exploring loneliness and social isolation in older adults with and without Alzheimer's disease.

Loneliness and Social Isolation Among Older Adults with and without Alzheimer's Disease and Related Dementia in the Last Years of Life

NIH-funded research University of California, San Francisco · NIH-10873311

This study looks at how feeling lonely or being socially isolated affects the health and happiness of older adults, especially those nearing the end of life, including those with Alzheimer's and related conditions, to help improve their overall well-being.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10873311 on NIH RePORTER

What this research studies

This research investigates how loneliness and social isolation affect the health and quality of life of older adults, particularly those in their last years of life. It distinguishes between loneliness, a subjective feeling, and social isolation, an objective lack of relationships. The study aims to understand the prevalence of these issues among older adults with and without Alzheimer's Disease and Related Dementia, and how they relate to health outcomes and healthcare utilization. By focusing on these social factors, the research seeks to highlight their importance alongside medical care for improving patient well-being.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 21 and above, particularly those with or without Alzheimer's Disease and Related Dementia.

Not a fit: Patients who are not older adults or do not have cognitive impairments or related dementias may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved support and interventions for older adults facing loneliness and social isolation, enhancing their quality of life.

How similar studies have performed: Previous research has indicated that addressing social factors like loneliness can significantly impact health outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.