NIH-funded research R01 grant

Exploring lifestyle factors and digital tools to assess Alzheimer's disease risk

Official title: Life's Essential 8, Digital Cognitive Markers, and Alzheimer's Disease Risk

Funded at Boston University Medical Campus · NIH-11133471 · Data updated 2026-11-12

This study is looking at how everyday habits can affect the risk of developing Alzheimer's disease in older adults, using fun tools like smartphone apps and wearables to keep track of changes in thinking over time, and it aims to help people understand how making healthier lifestyle choices might delay symptoms.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus
NIH-funded
Lab location1 site (Boston, United States)
Project startMay 15, 2025
Project endJanuary 31, 2030
Funding year2025
Award (this year)$441,612
NIH project number1R01AG086303-01A1
Project IDNIH-11133471 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals aged 65 and older who are interested in monitoring their cognitive health and lifestyle factors.

Less likely to help

Patients under the age of 65 or those with advanced Alzheimer's disease may not benefit from this research.

What this research studies

This research investigates how lifestyle factors, measured by Life's Essential 8, can influence the risk of developing Alzheimer's disease, particularly in older adults. It utilizes innovative digital tools, such as smartphone applications and wearable devices, to monitor cognitive changes over time. By analyzing data from a large cohort, the study aims to identify early signs of cognitive decline and understand how lifestyle modifications can potentially delay the onset of Alzheimer's symptoms. Participants will be engaged in regular assessments to track their cognitive health and lifestyle choices.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing or delaying Alzheimer's disease through lifestyle changes.

How similar studies have gone: Previous research has shown promise in using digital tools for cognitive assessment, but this specific approach combining lifestyle factors with digital markers is relatively novel.

Where this research is happening

  • Boston University Medical Campus
    Boston, United States
    Active

Researchers

  • Principal investigator: Liu, Chunyu — Boston University Medical Campus
  • Study coordinator: Liu, Chunyu

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.