Exploring how well-being can protect against cognitive decline and dementia risk
Well-being as a Protective Factor against Cognitive Decline and Dementia Risk
This study is looking at how feeling good and happy can help protect older adults, especially those with Alzheimer's or related conditions, from losing their memory and thinking skills over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10834222 on NIH RePORTER |
What this research studies
This research investigates the role of well-being as a protective factor against Alzheimer's Disease and Related Dementias (ADRD). It aims to identify various predictors of well-being that contribute to cognitive resilience in older adults, including those with ADRD-related neuropathology. The study will analyze existing longitudinal datasets to understand the relationship between well-being and cognitive decline, examining how these factors influence each other over time. The research will also involve training in advanced methodologies to ensure robust findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those at risk for or diagnosed with Alzheimer's Disease and Related Dementias.
Not a fit: Patients who are younger than 21 years old or do not have any risk factors for cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing well-being, potentially reducing the risk of cognitive decline and dementia in older adults.
How similar studies have performed: Previous research has shown promising results in understanding the impact of well-being on cognitive health, suggesting that this approach could yield valuable insights.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Willroth, Emily C — Washington University
- Study coordinator: Willroth, Emily C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.