Exploring how we switch between different ways of seeing the world
Official title: CRCNS: There and Back Again Linking Global Maps to First-Person Perspectives
Funded at University of California-Irvine · NIH-11103362 · Data updated 2026-11-12
This study is exploring how our brains switch between seeing the big picture and focusing on details, which could help us understand memory and navigation better, especially for people with Alzheimer's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | September 1, 2023 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $324,728 |
| NIH project number | 5R01NS135850-03 |
| Project ID | NIH-11103362 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals experiencing cognitive decline or memory issues, particularly those diagnosed with Alzheimer's disease.
✕Less likely to help
Patients with no cognitive impairments or those not affected by Alzheimer's disease may not receive direct benefits from this research.
What this research studies
This research investigates how our brains transition between viewing the world from a broad, map-like perspective and a close-up, first-person perspective. By using advanced neural network models and conducting experiments with both rodents and humans, the study aims to uncover the underlying neural mechanisms and environmental factors that facilitate this perspective switching. Patients may benefit from insights gained into cognitive functions related to navigation and memory, particularly in the context of Alzheimer's disease.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cognitive functions and lead to improved strategies for navigating challenges associated with Alzheimer's disease.
How similar studies have gone: Previous research has shown promise in understanding cognitive functions through similar multidisciplinary approaches, indicating potential for success in this area.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Krichmar, Jeffrey L — University of California-Irvine
- Study coordinator: Krichmar, Jeffrey L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.