Exploring how we switch between different ways of seeing the world

CRCNS: There and Back Again Linking Global Maps to First-Person Perspectives

NIH-funded research University of California-Irvine · NIH-11103362

This study is exploring how our brains switch between seeing the big picture and focusing on details, which could help us understand memory and navigation better, especially for people with Alzheimer's disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-11103362 on NIH RePORTER

What this research studies

This research investigates how our brains transition between viewing the world from a broad, map-like perspective and a close-up, first-person perspective. By using advanced neural network models and conducting experiments with both rodents and humans, the study aims to uncover the underlying neural mechanisms and environmental factors that facilitate this perspective switching. Patients may benefit from insights gained into cognitive functions related to navigation and memory, particularly in the context of Alzheimer's disease.

Who could benefit from this research

Good fit: Ideal candidates for participation are individuals experiencing cognitive decline or memory issues, particularly those diagnosed with Alzheimer's disease.

Not a fit: Patients with no cognitive impairments or those not affected by Alzheimer's disease may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of cognitive functions and lead to improved strategies for navigating challenges associated with Alzheimer's disease.

How similar studies have performed: Previous research has shown promise in understanding cognitive functions through similar multidisciplinary approaches, indicating potential for success in this area.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.