NIH-funded research R01 grant

Exploring how vision problems in kidney disease patients may lead to cognitive decline and dementia.

Official title: Understanding Vision Impairment in ESKD to Prevent Cognitive Impairment and Dementia/Alzheimer’s disease: the VIS-HD Cohort Study

Funded at New York University School of Medicine · NIH-11047340 · Data updated 2026-11-12

This study is looking at how vision problems might affect thinking skills in people with severe kidney disease, and it hopes to find ways to improve both vision and overall health for these patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine
NIH-funded
Lab location1 site (New York, United States)
Project startJanuary 1, 2025
Project endDecember 31, 2029
Funding year2025
Award (this year)$829,211
NIH project number1R01AG086252-01A1
Project IDNIH-11047340 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who are diagnosed with end-stage kidney disease and experiencing vision impairment.

Less likely to help

Patients without end-stage kidney disease or those who do not have vision impairment may not benefit from this research.

What this research studies

This research investigates the link between vision impairment and cognitive decline in patients with end-stage kidney disease (ESKD). It aims to identify the prevalence and causes of vision issues in this population, as well as the potential for reversing these impairments. The study will also explore the cognitive effects of vision loss and the barriers to effective vision screening and treatment. By understanding these factors, the research seeks to improve the overall health and quality of life for ESKD patients.

Why it matters

Potential benefit: If successful, this research could lead to improved screening and treatment strategies that may reduce the risk of cognitive decline and dementia in patients with ESKD.

How similar studies have gone: Previous research has indicated a strong association between vision impairment and cognitive decline in older adults, suggesting that this approach has potential for success.

Where this research is happening

  • New York University School of Medicine
    New York, United States
    Active

Researchers

  • Principal investigator: Mcadams Demarco, Mara a. — New York University School of Medicine
  • Study coordinator: Mcadams Demarco, Mara a.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.