Exploring how virtual reality can help understand learning differences in PTSD

Using novel virtual reality tasks to identify neural mechanisms of discrimination learning in PTSD

['FUNDING_R01'] · UNIVERSITY OF ROCHESTER · NIH-10953535

This study is exploring how people with PTSD can learn to tell the difference between safe and dangerous situations using virtual reality games, and it hopes to find new ways to help improve their understanding and treatment of the condition.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ROCHESTER (nih funded)
Locations1 site (ROCHESTER, UNITED STATES)
Trial IDNIH-10953535 on ClinicalTrials.gov

What this research studies

This research investigates how individuals with post-traumatic stress disorder (PTSD) learn to distinguish between safe and threatening cues in their environment using novel virtual reality tasks. Participants will engage in VR scenarios designed to assess their ability to recognize and respond to different cues associated with threat and reward. By examining brain activity during these tasks, the study aims to uncover the neural mechanisms that contribute to the difficulties faced by those with PTSD in processing contextual information. The findings could lead to better diagnostic tools and treatment strategies for PTSD.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults aged 21 and older who have been diagnosed with PTSD or have experienced trauma but do not have PTSD.

Not a fit: Patients who are under 21 years old or those without any history of trauma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals suffering from PTSD.

How similar studies have performed: While the use of virtual reality in psychological research is growing, this specific approach to studying discrimination learning in PTSD is relatively novel and has not been extensively tested.

Where this research is happening

ROCHESTER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.