Exploring how variations in DNA sequences affect biological functions
DMS/NIGMS 1: Multilayer network approach to tandem repeat variation in genomes
['FUNDING_R01'] · STATE UNIVERSITY OF NEW YORK AT BUFFALO · NIH-10919783
This study is looking at how certain repeated sections of our DNA affect our health and how they change in different environments, which could help us understand genetic factors that influence diseases and improve personalized medicine for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY OF NEW YORK AT BUFFALO (nih funded) |
| Locations | 1 site (AMHERST, UNITED STATES) |
| Trial ID | NIH-10919783 on ClinicalTrials.gov |
What this research studies
This research investigates the role of tandem repeat variations in the human genome and their impact on biological functions. By utilizing advanced computational methodologies and integrating various biological datasets, the study aims to identify which specific tandem repeats are functionally relevant and how they evolve under different environmental pressures. Patients may benefit from insights into genetic factors that influence health and disease, as the findings could lead to a better understanding of genetic functions and their implications for personalized medicine.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with genetic variations or conditions that may be influenced by tandem repeat variations in their genomes.
Not a fit: Patients with no known genetic variations or those not affected by conditions related to genetic functions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic variations that influence health, potentially leading to improved diagnostic and therapeutic strategies.
How similar studies have performed: Other research has shown success in understanding genetic variations and their functional implications, suggesting that this approach could yield valuable insights.
Where this research is happening
AMHERST, UNITED STATES
- STATE UNIVERSITY OF NEW YORK AT BUFFALO — AMHERST, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MASUDA, NAOKI — STATE UNIVERSITY OF NEW YORK AT BUFFALO
- Study coordinator: MASUDA, NAOKI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.