Exploring how vagus nerve stimulation may help improve cognitive function in older adults and those with Alzheimer's disease.
Mechanisms and therapeutic potential of vagus nerve stimulation in aging and Alzheimer’s disease
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-11093516
This study is looking at how a treatment called vagus nerve stimulation might help improve memory and thinking skills in older adults, especially those with Alzheimer's disease, by helping the brain work better.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-11093516 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of vagus nerve stimulation (VNS) on cognitive deficits associated with aging and Alzheimer's disease. It aims to understand how VNS can help restore the balance of brain signaling that is disrupted in older adults, potentially improving memory and executive functions. The study will involve assessing the impact of VNS on brain health and cognitive performance in individuals aged 65 and older, using a combination of clinical assessments and advanced imaging techniques.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are experiencing cognitive deficits or have a diagnosis of Alzheimer's disease.
Not a fit: Patients under the age of 65 or those without cognitive deficits or Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic options for enhancing cognitive function and slowing the progression of Alzheimer's disease in older adults.
How similar studies have performed: Previous studies have shown that vagus nerve stimulation can be effective in treating conditions like epilepsy and depression, suggesting potential for success in cognitive enhancement as well.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BIZON, JENNIFER LYNN — UNIVERSITY OF FLORIDA
- Study coordinator: BIZON, JENNIFER LYNN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.