Exploring how the embryonic vasopressin system influences brain development and behavior
Official title: Understanding the central embryonic vasopressin system
Funded at Kent State University · NIH-10580287 · Data updated 2026-11-12
This study is looking at how a special system in the brain that uses a hormone called vasopressin affects brain development and social behavior in male and female mice, which could help us understand similar issues in people with neuropsychiatric disorders.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kent State University NIH-funded |
| Lab location | 1 site (Kent, United States) |
| Project start | January 2, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $456,000 |
| NIH project number | 1R15HD110963-01 |
| Project ID | NIH-10580287 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with neuropsychiatric disorders that exhibit social behavior impairments.
✕Less likely to help
Patients with conditions unrelated to neurodevelopmental origins or social behavior may not receive benefit from this research.
What this research studies
This research investigates the role of the central embryonic vasopressin system in brain development and behavior, focusing on sex-specific differences. The study aims to define the structure of this system in both females and males, assess how vasopressin receptor signaling affects brain development, and explore its impact on social behavior. By using mice as a model, the research seeks to uncover mechanisms that may have implications for understanding neuropsychiatric disorders in humans. Patients may benefit from insights gained about the vasopressin system's role in social behavior and related conditions.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of neurodevelopmental disorders and inform treatment strategies for conditions linked to social behavior impairments.
How similar studies have gone: While the specific focus on the embryonic vasopressin system is novel, related research has shown success in understanding the role of vasopressin in social behavior and neurodevelopment.
Where this research is happening
-
Kent State University
Kent, United States Active
Researchers
- Principal investigator: Caldwell, Heather Kingsley — Kent State University
- Study coordinator: Caldwell, Heather Kingsley
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.