Exploring how the brain processes smells and movements together
Understanding the neuronal mechanisms of closed-loop olfaction
['FUNDING_R01'] · COLD SPRING HARBOR LABORATORY · NIH-10883618
This study is looking at how mice use their sense of smell while they move around, to see how their actions affect what they smell and how their brains learn to connect the two.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLD SPRING HARBOR LABORATORY (nih funded) |
| Locations | 1 site (COLD SPRING HARBOR, UNITED STATES) |
| Trial ID | NIH-10883618 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain integrates sensory information from smells with motor actions, specifically in mice. It focuses on understanding how movements influence the perception of odors and how the brain learns to predict the sensory outcomes of these actions. By using a novel task called the Smellocator, researchers will analyze how specific brain circuits respond to olfactory cues while the mice are actively moving. This approach aims to uncover the neuronal mechanisms that link olfaction and motor behavior in a closed-loop system.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals with conditions affecting sensory processing or motor control.
Not a fit: Patients with no sensory processing or motor control issues may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of sensory processing and lead to improved treatments for sensory-related disorders.
How similar studies have performed: Previous research has shown promising results in understanding sensory integration, but this specific approach using closed-loop olfaction is relatively novel.
Where this research is happening
COLD SPRING HARBOR, UNITED STATES
- COLD SPRING HARBOR LABORATORY — COLD SPRING HARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALBEANU, DINU FLORENTIN — COLD SPRING HARBOR LABORATORY
- Study coordinator: ALBEANU, DINU FLORENTIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.