Exploring how the brain influences social bonds
Understanding the neural basis of social attachment
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10880231
This study is looking at how certain hormones and genes affect the way we form close relationships, using prairie voles as a model, and it hopes to find new ways to help people with mental health issues that make it hard to connect with others.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10880231 on ClinicalTrials.gov |
What this research studies
This research investigates the neural and genetic mechanisms that underlie social attachment, which is crucial for forming relationships in humans. By studying prairie voles, which exhibit social monogamy and strong pair bonds, the research aims to uncover how specific hormones like vasopressin and oxytocin affect social behaviors. The study utilizes advanced genetic techniques to analyze these mechanisms, potentially leading to insights that could help treat mental illnesses characterized by disrupted social attachments. Patients may benefit from findings that could inform new therapeutic approaches for neuropsychiatric disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals experiencing social attachment issues or related neuropsychiatric disorders.
Not a fit: Patients without any social attachment difficulties or those not affected by neuropsychiatric conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for mental health conditions that impair social relationships.
How similar studies have performed: Previous research has shown promising results in understanding social attachment through similar hormonal and genetic approaches, indicating potential for success in this study.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MANOLI, DEVANAND SADANAND — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: MANOLI, DEVANAND SADANAND
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.