Exploring how temperature affects sensory receptors in insects
Official title: Understanding the Molecular Mechanisms of Thermoreceptors
Funded at Virginia Polytechnic Inst and St Univ · NIH-10998428 · Data updated 2026-11-12
This study looks at how temperature affects the behavior and body functions of mosquitoes and fruit flies, using special tools to understand how they sense heat, which could help us find better ways to control the diseases they spread.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Polytechnic Inst and St Univ NIH-funded |
| Lab location | 1 site (Blacksburg, United States) |
| Project start | January 23, 2025 |
| Project end | January 22, 2028 |
| Funding year | 2024 |
| Award (this year) | $45,503 |
| NIH project number | 1F31NS139648-01 |
| Project ID | NIH-10998428 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals interested in vector-borne disease prevention and those affected by diseases transmitted by mosquitoes.
✕Less likely to help
Patients who are not affected by vector-borne diseases or have no interest in insect-related health issues may not benefit from this research.
What this research studies
This research investigates how temperature influences the behavior and physiological processes of insects, particularly focusing on mosquitoes and fruit flies. By studying the molecular mechanisms of thermoreceptors, the project aims to understand how these insects respond to temperature changes, which is crucial for their survival and reproduction. The research utilizes advanced genetic tools, including CRISPR-Cas9 technology, to identify specific proteins and amino acids involved in temperature sensing. Insights gained from this study could lead to new strategies for controlling diseases transmitted by these insects.
Why it matters
Potential benefit: If successful, this research could lead to innovative methods for controlling vector-borne diseases like malaria and dengue.
How similar studies have gone: Previous research has shown success in understanding insect behavior through genetic studies, making this approach promising.
Where this research is happening
-
Virginia Polytechnic Inst and St Univ
Blacksburg, United States Active
Researchers
- Principal investigator: Huda, Ainul — Virginia Polytechnic Inst and St Univ
- Study coordinator: Huda, Ainul
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.