Exploring how syntocinon can reduce pain and opioid use
Opioid-Sparing and Pain-Reducing Properties of Syntocinon: A Dose-Effect Determination
This study is looking at how a medication called syntocinon, which is a form of oxytocin, might help relieve pain without the risk of becoming addicted to opioids, and it's for people who are dealing with acute pain.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11001140 on NIH RePORTER |
What this research studies
This research investigates the potential of syntocinon, a formulation of oxytocin, to alleviate pain while minimizing the risk of opioid misuse. By examining its effects in both animal models and human subjects, the study aims to determine the dose-response relationship of syntocinon in pain management. The approach includes assessing how syntocinon can enhance pain relief and reduce the likelihood of opioid addiction, providing a dual benefit for patients experiencing acute pain. Participants may receive syntocinon to evaluate its effectiveness in reducing pain sensitivity and opioid dependency.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing acute pain who are at risk of opioid misuse.
Not a fit: Patients who do not experience acute pain or have no history of opioid use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer pain management strategies that reduce reliance on opioids.
How similar studies have performed: Previous research has shown promising results with oxytocin in reducing pain and opioid use, suggesting this approach may be effective.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Berry, Meredith — University of Florida
- Study coordinator: Berry, Meredith
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.