Exploring how stress hormones affect Meniere's disease
Official title: Understanding the role of stress hormones in Meniere's disease
Funded at Creighton University · NIH-11084304 · Data updated 2026-11-12
This study is looking at how stress hormones might affect the inner ear and contribute to Meniere's disease, which causes hearing loss and dizziness, in hopes of finding new ways to help people with this condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Creighton University NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | May 6, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $183,750 |
| NIH project number | 5R21DC020983-02 |
| Project ID | NIH-11084304 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Meniere's disease who experience symptoms like hearing loss and vertigo.
✕Less likely to help
Patients without Meniere's disease or those whose symptoms are unrelated to stress may not benefit from this research.
What this research studies
This research investigates the connection between stress hormones and Meniere's disease, which causes hearing loss and vertigo. The study aims to understand how these hormones influence the production of endolymph, a fluid crucial for hearing and balance, by examining adrenergic hormone receptors in mice. Through various tests, including electrophysiological measures and histological analysis, researchers will assess how stress impacts inner ear function. The ultimate goal is to identify potential new treatments for Meniere's disease based on these findings.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that alleviate symptoms of Meniere's disease.
How similar studies have gone: While the specific connection between stress hormones and Meniere's disease is not extensively studied, related research has shown that stress can exacerbate various auditory disorders.
Where this research is happening
-
Creighton University
Omaha, United States Active
Researchers
- Principal investigator: Renauld, Justine Marie — Creighton University
- Study coordinator: Renauld, Justine Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.