Exploring how stress hormones affect Meniere's disease
Understanding the role of stress hormones in Meniere's disease
This study is looking at how stress hormones might affect the inner ear and contribute to Meniere's disease, which causes hearing loss and dizziness, in hopes of finding new ways to help people with this condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Creighton University NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11084304 on NIH RePORTER |
What this research studies
This research investigates the connection between stress hormones and Meniere's disease, which causes hearing loss and vertigo. The study aims to understand how these hormones influence the production of endolymph, a fluid crucial for hearing and balance, by examining adrenergic hormone receptors in mice. Through various tests, including electrophysiological measures and histological analysis, researchers will assess how stress impacts inner ear function. The ultimate goal is to identify potential new treatments for Meniere's disease based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Meniere's disease who experience symptoms like hearing loss and vertigo.
Not a fit: Patients without Meniere's disease or those whose symptoms are unrelated to stress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that alleviate symptoms of Meniere's disease.
How similar studies have performed: While the specific connection between stress hormones and Meniere's disease is not extensively studied, related research has shown that stress can exacerbate various auditory disorders.
Where this research is happening
Omaha, United States
- Creighton University — Omaha, United States (Active)
Researchers
- Principal investigator: Renauld, Justine Marie — Creighton University
- Study coordinator: Renauld, Justine Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.