Exploring how stress affects pregnancy outcomes in Black women

Understanding the contributions of stress reactivity to racial disparities in adverse placental and pregnancy outcomes

NIH-funded research Northwestern University at Chicago · NIH-11038042

This study is looking at how stress affects pregnancy health, especially for non-Hispanic Black women, to understand why they might face more challenges during pregnancy compared to non-Hispanic White women, and it uses real-time measurements to see how stress impacts their bodies and minds.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11038042 on NIH RePORTER

What this research studies

This research investigates the role of stress reactivity in contributing to higher rates of adverse pregnancy outcomes among non-Hispanic Black women compared to their non-Hispanic White counterparts. It focuses on understanding how chronic exposure to stressors throughout life, including racial and gender discrimination, impacts physiological and psychological responses during pregnancy. The study employs advanced methods such as ecological momentary assessments and intensive measurements of heart rate variability, blood pressure, and cortisol levels to capture how these women respond to stress in real-time. By examining these factors, the research aims to uncover the links between stress and pregnancy health.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant Black women who may experience high levels of stress due to various life circumstances.

Not a fit: Patients who are not pregnant or those who do not identify as Black may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions to reduce adverse pregnancy outcomes in Black women.

How similar studies have performed: Previous research has indicated that stress reactivity is linked to adverse health outcomes, but this specific focus on pregnancy outcomes in Black women is relatively novel.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.