NIH-funded research R21 grant

Exploring how socioeconomic challenges contribute to obesity

Official title: Bio-Social Pathways Linking Socioeconomic Adversity to Obesity

Funded at Pennsylvania State University, the · NIH-10909285 · Data updated 2026-11-12

This study is looking at how tough life experiences, especially for people from different racial and ethnic backgrounds, might lead to weight gain by affecting our biology, and it's for anyone interested in understanding the links between life challenges and obesity.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionPennsylvania State University, the
NIH-funded
Lab location1 site (University Park, United States)
Project startAugust 17, 2023
Project endJune 30, 2026
Funding year2024
Award (this year)$118,309
NIH project number5R21HL170280-02
Project IDNIH-10909285 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include African American adults who are experiencing socioeconomic challenges and are at risk for obesity.

Less likely to help

Patients who do not identify as African American or who do not face socioeconomic adversity may not benefit from this research.

What this research studies

This research investigates the connection between socioeconomic adversity and obesity, particularly among racial and ethnic minorities. By examining data from approximately 9,000 individuals across diverse cohorts, the study aims to understand how adverse life experiences may lead to biological changes that increase obesity risk. The researchers will focus on DNA methylation as a potential biological mechanism linking socioeconomic status to obesity and related health issues. This approach combines social and biological perspectives to provide a comprehensive understanding of the problem.

Why it matters

Potential benefit: If successful, this research could lead to targeted interventions that address the root causes of obesity in disadvantaged populations.

How similar studies have gone: Previous research has shown promising results in understanding the biological impacts of socioeconomic factors on health, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Pennsylvania State University, the
    University Park, United States
    Active

Researchers

  • Principal investigator: Fernandez-Rhodes, Lindsay — Pennsylvania State University, the
  • Study coordinator: Fernandez-Rhodes, Lindsay

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.