Exploring how social stress affects brain health in different racial groups
Official title: Uncovering Mechanisms of Racial Inequalities in ADRD: Psychosocial Risk and Resilience Factors for White Matter Integrity
Funded at University of Michigan at Ann Arbor · NIH-10931336 · Data updated 2026-11-12
This study is looking at how social stress, especially related to race, affects brain health in different racial groups, with the goal of finding ways to improve brain health and reduce the risk of Alzheimer's disease for everyone.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | January 10, 2024 |
| Project end | January 9, 2026 |
| Funding year | 2025 |
| Award (this year) | $41,843 |
| NIH project number | 5F31AG082506-02 |
| Project ID | NIH-10931336 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals from diverse racial backgrounds who are at risk for Alzheimer's disease and related dementias.
✕Less likely to help
Patients who do not have any risk factors for Alzheimer's disease or related dementias may not benefit from this research.
What this research studies
This research investigates the effects of social stressors, particularly those that are racially patterned, on the integrity of white matter in the brains of individuals across different racial groups. By analyzing data from two cohort studies, the project aims to identify how these stressors contribute to disparities in brain health and the risk of Alzheimer's disease and related dementias (ADRD). The research will utilize advanced neuroimaging techniques and statistical analyses to uncover potential modifiable factors that could help reduce these disparities. The findings may lead to targeted interventions that improve brain health outcomes for affected populations.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for reducing racial disparities in Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown that addressing social determinants of health can lead to improved outcomes in various health conditions, suggesting potential for success in this area as well.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Palms, Jordan D. — University of Michigan at Ann Arbor
- Study coordinator: Palms, Jordan D.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.