Exploring how social isolation affects Alzheimer's disease and related dementias

Project 4: Social isolation as a driver of AD/ADRD incidence and disparities

['FUNDING_P01'] · BOSTON UNIVERSITY MEDICAL CAMPUS · NIH-10934717

This study is looking at how being socially isolated might raise the chances of older adults developing Alzheimer's and other related memory issues, especially in different communities, and it will also explore ways to help people stay connected to reduce these risks.

Quick facts

Phase['FUNDING_P01']
Study typeNih_funding
SexAll
SponsorBOSTON UNIVERSITY MEDICAL CAMPUS (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10934717 on ClinicalTrials.gov

What this research studies

This research investigates the impact of social isolation on the incidence of Alzheimer's disease and related dementias (ADRD) among older adults. It aims to understand how limited social contact can increase the risk of developing these conditions, especially in diverse population groups. The study will also explore potential interventions to enhance social connections and reduce the risk of ADRDs. By examining the effects of social isolation before and during the pandemic, the research seeks to fill gaps in current knowledge and improve intervention strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who experience social isolation and are at risk for Alzheimer's disease or related dementias.

Not a fit: Patients who are not experiencing social isolation or who do not have risk factors for Alzheimer's disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective interventions that reduce the risk of Alzheimer's disease and related dementias by addressing social isolation.

How similar studies have performed: Previous research has indicated a correlation between social isolation and increased risk of dementia, suggesting that this approach may yield valuable insights.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease prevention, Alzheimer's disease and related dementia, Alzheimer's disease and related disorders, Alzheimer's disease or a related dementia, Alzheimer's disease or a related disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.