NIH-funded research NIH-funded research

Exploring how social factors influence aging in cancer survivors

Official title: Social Determinants of Health as Transducers of Cellular Aging: A New Multi-level Paradigm to Reduce Survivorship Disparities at the Intersection of Cancer and Aging

Funded at Georgetown University · NIH-10901922 · Data updated 2026-11-12

This study is looking at how things like income, education, and community can affect how quickly older cancer survivors age, especially for those from different racial and ethnic backgrounds, to help improve their care and health outcomes.

More Aging research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionGeorgetown University
NIH-funded
Lab location1 site (Washington, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2030
Funding year2024
Award (this year)$888,061
NIH project number5R35CA283926-02
Project IDNIH-10901922 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older cancer survivors, particularly those aged 65 and older, especially from Hispanic and Black communities.

Less likely to help

Patients who are younger than 65 or those without a history of cancer may not receive direct benefits from this research.

What this research studies

This research investigates the complex relationships between social determinants of health and cellular aging in older cancer survivors, particularly focusing on racial and ethnic disparities. It aims to understand how these social factors accelerate aging processes and impact survivorship outcomes. By integrating perspectives from oncology and geroscience, the study will utilize advanced methodologies, including transcriptomic analysis, to uncover the mechanisms at play. The goal is to provide evidence that can guide better care for older cancer survivors, especially those from underrepresented communities.

Why it matters

Potential benefit: If successful, this research could lead to improved care strategies that address the unique needs of older cancer survivors, particularly among racial and ethnic minorities.

How similar studies have gone: Other research has shown success in addressing health disparities through similar multi-level approaches, indicating potential for impactful findings in this area.

Where this research is happening

  • Georgetown University
    Washington, United States
    Active

Researchers

  • Principal investigator: Mandelblatt, Jeanne — Georgetown University
  • Study coordinator: Mandelblatt, Jeanne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.