NIH-funded research NIH-funded research

Exploring how sex and gender affect lung disease

Official title: Mentoring in Patient Oriented Research in Lung Disease through a Sex and Gender Lens

Funded at Brigham and Women's Hospital · NIH-11004143 · Data updated 2026-11-12

This study is looking at how lung disease, like COPD, affects men and women differently, so we can better understand their unique risks, symptoms, and treatment responses, while also helping new researchers learn how to consider these differences in their work.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startJanuary 1, 2024
Project endDecember 31, 2028
Funding year2025
Award (this year)$128,650
NIH project number5K24HL171900-02
Project IDNIH-11004143 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with chronic obstructive pulmonary disease (COPD) who are interested in how their sex and gender may influence their condition.

Less likely to help

Patients with lung diseases unrelated to COPD or those who do not identify with the biological sex or gender constructs being studied may not benefit from this research.

What this research studies

This research investigates the differences in lung disease between males and females, focusing on how these differences impact risk, progression, symptoms, and treatment responses. By utilizing advanced data science techniques, the project aims to analyze genetic and biological factors that contribute to these disparities. The program also emphasizes mentoring new researchers in understanding and applying sex and gender considerations in their work, particularly in the context of chronic obstructive pulmonary disease (COPD). Through this approach, the research seeks to translate findings into practical clinical innovations that can improve patient care.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatments for lung diseases based on sex and gender differences.

How similar studies have gone: Previous research has shown promising results in understanding sex and gender differences in other health conditions, suggesting potential for success in this novel approach to lung disease.

Where this research is happening

  • Brigham and Women's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Demeo, Dawn L — Brigham and Women's Hospital
  • Study coordinator: Demeo, Dawn L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.