Exploring how sex and gender affect liver cancer risk and survival

Determining the influence of sex and gender in hepatocellular carcinoma risk and survival

['FUNDING_CAREER'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10862801

This study looks at how being male or female affects the risk and survival rates of liver cancer in people with cirrhosis, hoping to find ways to improve prevention and treatment based on these differences.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorUT SOUTHWESTERN MEDICAL CENTER (nih funded)
Locations1 site (DALLAS, UNITED STATES)
Trial IDNIH-10862801 on ClinicalTrials.gov

What this research studies

This research investigates the differences in risk and survival rates of hepatocellular carcinoma (HCC) based on sex and gender among patients with cirrhosis. It aims to understand how biological factors related to sex and social or behavioral factors related to gender contribute to these disparities. By analyzing data from over 4,000 patients, the study will assess the impact of these factors on HCC risk and survival outcomes. The findings could help tailor prevention and treatment strategies for liver cancer based on sex and gender differences.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with cirrhosis who are at risk for developing hepatocellular carcinoma.

Not a fit: Patients without cirrhosis or those who do not have hepatocellular carcinoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for liver cancer that are tailored to the specific needs of different genders.

How similar studies have performed: Previous research has shown that sex and gender can significantly influence cancer outcomes, suggesting that this approach could yield valuable insights.

Where this research is happening

DALLAS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.