Exploring how rare genetic variations affect brain structure and mental health risks.
Understanding Rare Genetic Variation and Disease Risk: A Global Neurogenetics Initiative
This study is looking at how certain genetic changes might affect brain development and behavior in people with neurodevelopmental psychiatric disorders, and it's for anyone interested in understanding the links between genetics and mental health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sainte-Justine University Hospital Ctr NIH-funded |
| Lab location | 1 site (Montreal, Canada) |
| Project ID | NIH-11080342 on NIH RePORTER |
What this research studies
This research investigates the impact of copy number variants (CNVs) on neurodevelopmental psychiatric disorders by analyzing a large dataset of neuroimaging and genetic information. The study aims to understand how these genetic variations influence brain architecture and function, as well as the behavioral features associated with them. By collaborating across multiple sites in the USA, Canada, and Norway, the research will utilize advanced imaging techniques and statistical models to uncover the relationships between genetic variations and mental health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with neurodevelopmental psychiatric disorders, particularly those with identified copy number variants.
Not a fit: Patients without neurodevelopmental psychiatric disorders or those without identifiable genetic variations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals with neurodevelopmental psychiatric disorders.
How similar studies have performed: Previous research has shown promising results in understanding genetic influences on brain structure and function, suggesting that this approach could yield valuable insights.
Where this research is happening
Montreal, Canada
- Sainte-Justine University Hospital Ctr — Montreal, Canada (Active)
Researchers
- Principal investigator: Jacquemont, Sebastien — Sainte-Justine University Hospital Ctr
- Study coordinator: Jacquemont, Sebastien
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.