Exploring how racial trauma affects mothers and infants during pregnancy.
The Impact of Transgenerational Racial Trauma on Epigenetic Modifications in the Mother-Infant Dyad during Pregnancy. Comparisons Between Caucasian and African American Populations
['FUNDING_R01'] · MOREHOUSE SCHOOL OF MEDICINE · NIH-10853049
This study is looking at how the experiences of racial trauma can affect the health of African American mothers and their babies during pregnancy, focusing on how these experiences might change the way their bodies work and impact their immune systems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MOREHOUSE SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-10853049 on ClinicalTrials.gov |
What this research studies
This research investigates the biological effects of transgenerational racial trauma on African American mothers and their infants during pregnancy. It focuses on how structural racism and discrimination have lasting impacts on health outcomes, particularly in maternal and infant health. By examining epigenetic modifications at the maternal-fetal interface, the study aims to understand how these changes may influence immune cell development and signaling in both the mother and the developing fetus. The research utilizes advanced techniques to analyze biological markers related to these epigenetic changes.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American women who are pregnant or planning to become pregnant.
Not a fit: Patients who are not of African American descent or who are not currently pregnant may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes for African American mothers and infants by addressing the underlying biological impacts of racial trauma.
How similar studies have performed: While the specific focus on transgenerational racial trauma is relatively novel, there is growing evidence from other studies indicating that epigenetic changes can significantly impact health outcomes.
Where this research is happening
ATLANTA, UNITED STATES
- MOREHOUSE SCHOOL OF MEDICINE — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JOHNSON, ERICA L — MOREHOUSE SCHOOL OF MEDICINE
- Study coordinator: JOHNSON, ERICA L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.