Exploring how race and social factors affect bladder cancer outcomes
Official title: Racial and social contextual factors in relation to epigenome and bladder cancer outcome
Funded at Texas Southern University · NIH-10932913 · Data updated 2026-11-12
This study is looking at how race and social factors affect bladder cancer and aims to help underserved communities by improving cancer care and education, so that everyone has a better chance at treatment and recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Southern University NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 21, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $36,171 |
| NIH project number | 5P20CA284967-02 |
| Project ID | NIH-10932913 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include African American individuals diagnosed with bladder cancer or those at risk for the disease.
✕Less likely to help
Patients who do not identify as African American or who do not have bladder cancer may not receive direct benefits from this research.
What this research studies
This research investigates the impact of racial and social contextual factors on the epigenome and outcomes for patients with bladder cancer. It aims to establish a collaborative effort between Texas Southern University and Baylor College of Medicine to address cancer health disparities, particularly in underserved populations. The project will focus on developing a cancer research program that emphasizes community engagement and education, while also exploring the biological aspects of cancer treatment and access to care. By leveraging the strengths of both institutions, the research seeks to improve understanding and outcomes for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better health outcomes for bladder cancer patients, particularly within minority communities.
How similar studies have gone: Previous research has shown success in addressing cancer health disparities through community engagement and collaborative efforts, indicating a promising approach for this project.
Where this research is happening
-
Texas Southern University
Houston, United States Active
Researchers
- Principal investigator: Solitare, Laura — Texas Southern University
- Study coordinator: Solitare, Laura
Related research
Other NIH-funded projects on the same topics.
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Population modeling to reduce bladder cancer burden
Aimed at predicting and guiding effective, population-based ways to prevent and control bladder cancer.
-
Blocking a new immune checkpoint in bladder cancer
Researchers are trying medicines that block a newly found immune pathway to help people with bladder cancer, especially those whose tumors do not respond to current immunotherapy.
-
Nrf2 in T cells and how it could boost immune power against bladder cancer
A small grant will explore how a T-cell protein called Nrf2 affects muscle-invasive bladder cancer and whether targeting it could help patients respond better to immune therapies.
-
Understanding why bladder cancer spreads and resists treatment
This grant studies how advanced bladder cancer changes and spreads across the body, aiming to uncover why it’s hard to treat.
-
Molecular clues to bladder cancer cell changes and therapy response
This NIH grant looks at how bladder cancer cells change their identity and how that affects response to treatment, with a focus on aggressive neuroendocrine variants.
-
Repurposing spironolactone to treat bladder cancer inside the bladder
Aims to repurpose spironolactone as an intravesical treatment for non-muscle invasive bladder cancer to help prevent recurrence and progression.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.