Exploring how protein methylation affects cell functions and disease.
Interrogating Complex Methylome Network with Integrated Chemical Biology Tools
This study is looking at how a special process called protein methylation affects how cells act and respond, which could help us understand diseases better and find new ways to treat them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11075792 on NIH RePORTER |
What this research studies
This research investigates the role of protein methylation, a key epigenetic modification, in determining how cells behave and respond to their environment. By developing advanced chemical biology tools, the team aims to uncover previously hidden methylation events and their effects on gene regulation and protein function. Patients may benefit from a better understanding of how these processes contribute to various diseases, potentially leading to new therapeutic strategies. The research focuses on the complex interactions within the methylome, which is crucial for understanding cellular identity and function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions influenced by epigenetic mechanisms, such as certain cancers or genetic disorders.
Not a fit: Patients with conditions unrelated to epigenetic changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for diseases linked to epigenetic changes.
How similar studies have performed: Previous research has shown promise in understanding epigenetic modifications, suggesting that this approach could yield significant insights.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Luo, Minkui — Sloan-Kettering Inst Can Research
- Study coordinator: Luo, Minkui
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.