Exploring how propionate metabolism affects aging
Official title: Investigating the link between propionate metabolism and aging
Funded at Weill Medical Coll of Cornell Univ · NIH-10985616 · Data updated 2026-11-12
This study is looking at how the way our bodies process a substance called propionate might affect how we age and why some people get age-related diseases like cancer and diabetes more quickly, so we can better understand the aging process and help everyone stay healthier longer.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $101,925 |
| NIH project number | 1K99AG084860-01A1 |
| Project ID | NIH-10985616 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults who may be experiencing age-related health issues or metabolic dysfunction.
✕Less likely to help
Patients who are not experiencing aging-related conditions or metabolic issues may not benefit from this research.
What this research studies
This research investigates the relationship between propionate metabolism and the aging process. It aims to understand why some individuals age more rapidly and are more prone to age-related diseases like cancer and diabetes. By examining how metabolic dysfunction influences cellular processes and the accumulation of certain metabolites, the study seeks to identify key metabolic pathways that contribute to aging. The research will involve analyzing how changes in propionate metabolism may impact cellular function and aging.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating age-related diseases.
How similar studies have gone: Previous research has shown promising results in understanding metabolic pathways related to aging, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Li, Zhongchi — Weill Medical Coll of Cornell Univ
- Study coordinator: Li, Zhongchi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.