Exploring how propionate metabolism affects aging

Investigating the link between propionate metabolism and aging

['FUNDING_CAREER'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-10985616

This study is looking at how the way our bodies process a substance called propionate might affect how we age and why some people get age-related diseases like cancer and diabetes more quickly, so we can better understand the aging process and help everyone stay healthier longer.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorWEILL MEDICAL COLL OF CORNELL UNIV (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10985616 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between propionate metabolism and the aging process. It aims to understand why some individuals age more rapidly and are more prone to age-related diseases like cancer and diabetes. By examining how metabolic dysfunction influences cellular processes and the accumulation of certain metabolites, the study seeks to identify key metabolic pathways that contribute to aging. The research will involve analyzing how changes in propionate metabolism may impact cellular function and aging.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who may be experiencing age-related health issues or metabolic dysfunction.

Not a fit: Patients who are not experiencing aging-related conditions or metabolic issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing or treating age-related diseases.

How similar studies have performed: Previous research has shown promising results in understanding metabolic pathways related to aging, suggesting that this approach could yield valuable insights.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Adult-Onset Diabetes Mellitus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.