NIH-funded research NIH-funded research

Exploring how plant glutamate receptors help plants communicate and adapt.

Official title: Merging Signaling with Structure: Functions and Mechanisms of Plant Glutamate Receptor Ion Channels, and their implications for the evolution of aminoacid based ion-signaling systems

Funded at Univ of Maryland, College Park · NIH-11051831 · Data updated 2026-11-12

This study looks at how plants use special receptors to send signals between their cells, helping them adapt to tough conditions like being eaten by insects or dealing with extreme temperatures, and it’s for anyone interested in understanding how plants communicate and survive in their environment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniv of Maryland, College Park
NIH-funded
Lab location1 site (College Park, United States)
Project startMarch 8, 2024
Project endDecember 31, 2028
Funding year2025
Award (this year)$348,581
NIH project number5R35GM152091-02
Project IDNIH-11051831 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research include agricultural scientists, plant biologists, and farmers interested in crop resilience.

Less likely to help

Patients with no interest or involvement in plant biology or agriculture may not receive any benefit from this research.

What this research studies

This research investigates the unique ways plants use glutamate receptors to communicate between their cells, despite lacking a nervous system. By studying these receptors, which generate electrical and calcium signals, the research aims to understand their roles in plant adaptation to environmental challenges such as herbivory and extreme temperatures. The project employs advanced techniques like cryo-electron microscopy to reveal the structure and function of these receptors, providing insights into their evolutionary significance and physiological roles.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of plant resilience and adaptation, potentially leading to improved agricultural practices.

How similar studies have gone: Other research has shown success in understanding ion signaling in plants, but this specific approach to glutamate receptors is relatively novel.

Where this research is happening

  • Univ of Maryland, College Park
    College Park, United States
    Active

Researchers

  • Principal investigator: Feijo, Jose a — Univ of Maryland, College Park
  • Study coordinator: Feijo, Jose a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.