Exploring how plant compounds can improve brain health and resilience.
Mechanism based evaluation of botanical bioactive compounds enhancing neurological resilience (Project 2)
This study is looking at how two natural supplements, Centella asiatica and Withania somnifera, might help improve brain health and support mental well-being, so people can learn more about how these plants could boost their cognitive abilities and emotional resilience.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10875568 on NIH RePORTER |
What this research studies
This research investigates the effects of botanical dietary supplements, specifically Centella asiatica and Withania somnifera, on neurological health. By using various laboratory techniques, including neuron assays and brain slice studies, the research aims to identify active compounds in these plants and understand their mechanisms of action. The study will assess how these compounds influence neuronal health, antioxidant responses, and vascular function, which are crucial for maintaining cognitive abilities and emotional well-being. Patients may benefit from insights into how these natural products can enhance brain resilience and overall mental health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in alternative therapies for improving brain health, particularly those experiencing cognitive decline or mood disorders.
Not a fit: Patients who are not interested in botanical supplements or those with severe neurological conditions requiring immediate medical intervention may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new natural treatments that enhance cognitive function and emotional resilience in patients.
How similar studies have performed: Previous studies have shown promising results with similar botanical compounds in enhancing cognitive function and mood, suggesting potential for success in this research.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Kretzschmar, Doris — Oregon Health & Science University
- Study coordinator: Kretzschmar, Doris
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.