Exploring how placental gene activity affects newborn metabolism and childhood asthma.
The association of placental gene expression and newborn metabolic profiles in understanding childhood asthma pathogenesis
This study is looking at how genes in the placenta and the metabolism of newborns are connected to the risk of developing asthma in childhood, with the hope of finding ways to help kids who might be at risk.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11034681 on NIH RePORTER |
What this research studies
This research investigates the relationship between gene expression in the placenta and metabolic profiles in newborns to better understand the development of childhood asthma. By analyzing how genetic and environmental factors interact, the study aims to identify specific pathways that may contribute to asthma risk. The researchers will focus on the metabolic profiles of newborns and how these relate to placental gene activity, potentially uncovering critical insights into asthma pathogenesis. This approach could lead to targeted interventions for at-risk children based on their metabolic and genetic profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research include newborns and infants up to 4 weeks old, particularly those with a family history of asthma or other respiratory issues.
Not a fit: Patients who are older than 11 years or those without any family history of asthma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and managing childhood asthma by identifying at-risk newborns early.
How similar studies have performed: Previous research has shown promising results in understanding the genetic and metabolic factors associated with asthma, suggesting that this approach could yield valuable insights.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Snyder, Brittney M — Vanderbilt University Medical Center
- Study coordinator: Snyder, Brittney M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.